Pletal 100 Mg Tablets

The apparent elimination pletal of cilostazol is Pletal a full list of excipients, see section 6. Date ppletal revision of the text. Therefore, you should only stop taking Pletal if you notice side effects requiring pletal medical attention see section 4 or if your doctor tells you to. Uric acid level increased, blood urea increased, pletal, blood creatinine increased. Driving and using machines Pletal may cause dizziness. During treatment with Pletal pletal sure that If you need to have surgery including having teeth removed, tell your doctor or dentist that you are taking Pletal. Caution should be exercised when co-administering cilostazol with any other agents that inhibit platelet aggregation. Caution is needed when co-administering cilostazol with any other agent which has the potential to reduce blood pressure due to the possibility that there may be an additive pletal effect with a reflex tachycardia. An increase in the frequency of diarrhoea plftal palpitation has been found in patients older than 70 years. Do not use Pletal after the expiry date which is stated on the carton and blister after "EXP". Pletal NOT take a double dose to make up for a forgotten tablet. To pletal a medicine you must sign plteal and log in. Following 24 weeks treatment, cilostazol mg b. Pletal tablets should be taken 30 minutes before breakfast and the evening meal. Cytochrome P enzyme substrates. All healthy subjects in the study had a prolongation of bleeding time pletal clopidogrel alone and concomitant administration with cilostazol did not result plwtal a significant additional effect on bleeding time. In total, 1, patients with intermittent claudication and no heart failure have been treated with cilostazol or placebo for up to three years. The suitability of treatment with cilostazol should be carefully considered alongside other treatment options such as revascularisation. Administration of a single dose of mg cilostazol with ml grapefruit juice an inhibitor of intestinal CYP3A4 did not have a notable effect on the pharmacokinetics of cilostazol, pletal. The usual dose is two 50 mg tablets twice a day morning and evening. Cilostazol is eliminated predominantly by metabolism and subsequent urinary excretion of metabolites.

The dehydro metabolite and 4'-trans-hydroxy metabolite are Pletal may cause dizziness. The clinical significance is unknown. This site uses cookies. You may need to have some blood tests and your doctor will decide on your further treatment. Before you start taking Pletal, please tell your doctor if you are taking:. As with other positive inotropic and vasodilator agents, cilostazol produced cardiovascular lesions in dogs. Last updated on eMC: It may harm them, even if their symptoms are the same as yours. Pletal is for second-line use, in patients in whom lifestyle modifications including stopping smoking and [supervised] exercise programs and other appropriate interventions have failed to sufficiently improve their intermittent claudication symptoms. Pletal may do the same to pletal medicines. This information is for educational purposes only, and not meant to provide medical advice, treatment, or diagnosis. Renal failure, renal impairment Haematuria, pollakiuria. Lactation The transfer of cilostazol to breast pletal has been reported in animal studies. It is written for patients and gives information about taking or using a medicine. You can also report side effects directly via the Yellow Card Scheme at: The following side effects have been reported for Pletal. Stop taking Pletal and contact a doctor or go to the nearest hospital immediately. Find out more here. In a single-dose clinical study, no inhibition of the metabolism of warfarin pletal an effect on the coagulation parameters PT, aPTT, bleeding time was observed. Hepatic impairment No dosage adjustment is necessary in patients with mild hepatic disease. A meta-analysis based on weighted mean differences across the nine studies indicated that there was a significant pletal overall post-baseline improvement of 42 m in maximal walking distance ACD for cilostazol mg pletal. In rats dosed during pregnancy, foetal weights were decreased. Sign Up Log In Cancel.

Hepatic impairment No dosage adjustment is necessary in patients with mild hepatic disease. The information contained herein is not intended to cover all possible uses, directions, precautions, pletal, pletal, drug interactions, allergic reactions, or adverse effects. The pharmacokinetics of cilostazol and its metabolites were not significantly affected by age or gender in healthy subjects aged between years. There are no adequate data in the use of cilostazol in pletal women. If any of the side effects gets serious, pletal, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. To bookmark a medicine you must sign up and log in. Headache Dizziness Uncommon Unknown. If you forget to pletal Pletal If you miss a dose, do not worry; wait until the next dose to take your next tablet and then carry on as normal. General disorders and administration site conditions. Very common side effects affecting more than 1 in 10 people headache abnormal stools diarrhoea Common side effects affecting less than 1 pletal 10, but more than 1 in people fast heart beat heart pounding palpitation chest pleta, dizziness sore throat pletal pletwl rhinitis abdominal pain abdominal discomfort indigestion feeling or being sick nausea or vomiting loss of appetite anorexia excessive burping or wind flatulence swelling of ankles, feet or face rash or changes in appearance of the skin itchy skin patchy bleeding in the skin general weakness Uncommon side effects affecting less than 1 inbut more than 1 in 1, people heart attack irregular heart beat new or worsening heart problems that can cause shortness of breath or ankle swelling pneumonia cough chills unexpected bleeding tendency pletal bleed e. Such lesions were not seen in pletal or monkeys and are considered species specific. Cilostazol mg-TEV, white, round. The expiry date refers to the last date of the month. Cilostazol is eliminated predominantly by metabolism and subsequent urinary excretion of metabolites. B01A C From data generated in nine placebo-controlled studies where 1, pletal were exposed to cilostazolit has been demonstrated that cilostazol improves exercise capacity as judged by changes in Absolute Claudication Distance Lpetal, or maximal walking distance and Initial Claudication Distance ICDor pain-free walking distance upon treadmill testing. Qualitative and quantitative composition 3. It has several actions which include widening of some pketal vessels and reducing the clotting activity clumping of some blood cells called platelets inside your vessels. Pletal 50 mg-MYL, white, pletal, round. The other ingredients are maize starch, microcrystalline cellulose, carmellose calcium, hypromellose and magnesium stearate. Respiratory, thoracic and mediastinal disorders. Cilostazol is not a substitute for such treatments. Antithrombotic agents, platelet aggregation inhibitor excl. You have been prescribed Pletal for "intermittent claudication".

During treatment with Pletal make sure that If you need to have surgery including having teeth removed, tell your doctor or dentist that you are taking Peltal. If your blood pressure falls too low, this could cause a fast heartbeat. Find out more here. If you feel dizzy after taking Pletal tablets, DO NOT drive and do not use any tools or machines and pletal your doctor or pharmacist. This site uses cookies. Such lesions were not seen in rats or monkeys and are considered species specific. Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. Cytochrome P enzyme inducers. It may still be all right for you to take the above mentioned medicines and Pletal together and your doctor will be able to decide what is suitable for you. To email a medicine you must sign up and log in. No dosage adjustment is necessary in patients with mild hepatic disease. Consideration should be given to monitoring the bleeding time at intervals. Very common side effects affecting more than 1 pletal 10 people plwtal abnormal stools diarrhoea Common side effects affecting less than 1 in 10, but more than 1 in people fast heart beat heart pounding palpitation pletal pain dizziness sore throat runny nose rhinitis abdominal pain pleta, discomfort indigestion feeling or being sick nausea or vomiting loss of appetite anorexia excessive burping or wind flatulence swelling of ankles, feet or face rash or changes in appearance of the skin itchy skin patchy bleeding in the skin general weakness Uncommon side effects affecting less than 1 inbut more than 1 in 1, people heart attack irregular heart beat new or worsening heart problems that can cause shortness of breath or ankle swelling pneumonia cough chills unexpected bleeding tendency to bleed e. The usual dose is two 50 mg tablets twice a day morning poetal evening. Hepatitis, hepatic function abnormal, jaundice. Pletal mg tablets. This medicinal product is subject to additional monitoring. Other potential interactions Caution is needed when co-administering cilostazol with any other agent which has the potential to reduce blood pressure due to the possibility that there may be an additive hypotensive effect with a reflex tachycardia, pletal. There are no data in patients with moderate to severe hepatic impairment and since cilostazol is extensively metabolised by hepatic enzymes, the medicine must not be used in such patients pletal section 4. The C max of cilostazol and its primary circulating metabolites increase less than pletap with increasing doses. John's wort on cilostazol pharmacokinetics has not been evaluated. Pletal must not be used during pregnancy see section 4. Do not use Pletal after the expiry date which is stated on the carton and blister after "EXP", pletal. Marketing authorisation number s 9. Cilostazol mg-MYL, white, round.

Pletal

Pletal pletal not suitable for children. Find out more here. In addition to reporting episodes of bleeding and easy bruising, patients should be warned ;letal promptly report any other signs which might pletal suggest the early development of blood dyscrasia such as pyrexia and sore throat. An increase in oletal frequency of diarrhoea and palpitation has been found in patients older than 70 years. Cytochrome P enzyme substrates. Reporting of suspected adverse reactions. Uric acid level increased, blood urea increased, blood creatinine increased. Rash, pruritus Eczema, skin eruptions, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria. Cilostazol mg-TEV, white, round. Clopidogrel and other antiplatelet drugs Concomitant pltal of cilostazol and clopidogrel did not have any effect on platelet count, prothrombin time PT or pletal partial thromboplastin time aPTT. How to store Pletal 6. Eye haemorrhage, epistaxis, gastrointestinal haemorrhage, haemorrhage unspecified, orthostatic hypotension Hot flushes, hypertension, hypotension, cerebral haemorrhage, pulmonary haemorrhage, muscle haemorrhage, respiratory tract haemorrhage, subcutaneous haemorrhage. Therefore, drugs pletzl CYP3A4 e. Patients should be warned to report any episode of bleeding pletal easy bruising whilst on therapy. Oral Anticoagulants like warfarin. The expiry date refers to the last date of the month. Rhinitis, pharyngitis Pletal, pneumonia, cough. Caution is advised when cilostazol pletal co-administered with CYP3A4 substrates with a narrow therapeutic index e. Cilostazol 50 mg-MYL, white, round. If you stop taking Pletal the pain in your legs may come back or get worse, pletal. Information on acute overdose in humans is limited. Cilostazol and several of its metabolites are phosphodiesterase III inhibitors which suppress cyclic AMP degradation, resulting in increased cAMP in a variety petal tissues including platelets and blood vessels.

Refer also to section 4. They may either increase the side effects of Pletal or make Pletal less effective. The following side effects have been reported during the use of Pletal but it is not known how frequently they may occur: Chest pain, asthenia Chills, malaise Pyrexia, pain. DO NOT take a double dose to make up for a forgotten tablet. The pletal contained herein is not pletal to cover all possible uses, directions, precautions, warnings, pleta interactions, allergic reactions, or adverse effects. Cilostazol mg-TEV, white, round. No effect on fertility was observed in rats or pletal non-human primates. However, pletal, your pleal may prescribe a lower dose if you are taking other medicines which may interfere with the effect of Pletal. Pletal may do the same to other medicines, pletal. There have been rare pletal very rare reports plletal haematological abnormalities including thrombocytopenia, leucopenia, agranulocytosis, pancytopenia and aplastic anaemia see section 4. Cilostazol 50 mg-MYL, white, round. It may still be all right for you to petal the above pldtal medicines and Pletal together and your doctor will be able to decide what is suitable for you. Investigation of QTc in dogs and monkeys showed no prolongation after administration of cilostazol or its metabolites, pletal. This will allow quick identification of new safety information. The increase in heart rate associated with cilostazol is approximately 5 to 7 bpm; in patients at risk this consequently may induce angina pectoris.

Peripheral Arterial Disease

Other potential interactions Caution poetal needed when co-administering cilostazol with any other agent which has the potential to reduce blood pressure due to the possibility that there may be an additive hypotensive effect with a reflex tachycardia. There are no adequate data in the use of cilostazol in pregnant women. Cilostazol reversibly impaired fertility of female mice but not in pletal animal species see section 5. Cilostazol should be taken 30 minutes before breakfast pletap the evening meal. If any of the side effects gets serious, or if you notice any pletal effects not listed in this leaflet, please tell your doctor or pharmacist. Healthcare professionals are asked to report any suspected adverse reactions. Following pletal doses of cilostazol mg twice daily in patients with peripheral vascular disease, steady state is achieved within lletal days. Pletal P CYP enzyme inhibitors. Marketing authorisation number s 9. In a single-dose clinical study, no inhibition of the metabolism of warfarin or pletap effect on the coagulation parameters PT, aPTT, bleeding time was observed. Before you start taking Pletal pletal tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Taking other medicines Before you start taking Pletal please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, pletal, including medicines obtained without a prescription. Neither Everyday Health nor its licensor assume any responsibility for any aspect of healthcare administered with the aid of the information provided. If your blood pressure falls too low, this could cause a fast heartbeat. Administration of a single dose of mg cilostazol with ml grapefruit juice an inhibitor of intestinal Pletaal did not have a notable effect on the pharmacokinetics of cilostazol. To view the changes to a medicine you must sign up and log in. Marketing authorisation holder 8. In such cases, a cilostazol dosage of 50 mg twice plletal is recommended see section 4. If you miss a dose, do not worry; wait until the next dose to take your next tablet and pleatl carry on as normal.

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If you have any questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Cilostazol mg-MYL, pletal, round. A clinically relevant effect on cilostazol is still possible at higher quantities of grapefruit juice. By continuing to browse the site you are agreeing to our policy on the use of cookies. If you miss a dose, do not worry; wait until the next dose to take your next tablet and then carry on as normal. What Is Cilostazol Pletal? The information on this page has been compiled for use by healthcare practitioners and consumers in the United States and therefore neither Everyday Health or its licensor warrant that uses outside of the United States are appropriate, pletal, unless specifically indicated oletal. One tablet contains mg of cilostazol, pletal. In a clinical study in healthy subjects, cilostazol given mg b. Patients should be observed and given supportive treatment. Remember to take the pack with you so that it is clear what medicine you have taken. A randomized, double-blind, placebo-controlled Phase IV study was conducted to assess the long-term effects of plteal, with focus on mortality and safety. Every effort has been made to ensure that the pletal provided by on this page is accurate, up-to-date, pletal complete, but no guarantee is made to that effect. Cilostazol 50 mg-APO, white, round. Read Next Cilostazol Pletal.

Eye haemorrhage, epistaxis, gastrointestinal haemorrhage, haemorrhage unspecified, orthostatic hypotension Hot flushes, hypertension, hypotension, cerebral haemorrhage, pulmonary haemorrhage, muscle haemorrhage, respiratory tract haemorrhage, subcutaneous haemorrhage. Very common Common Gastritis. There are no special dosage requirements for the elderly. Pletal mg tablets. No dosage adjustment is necessary in patients with mild hepatic disease. Bleeding time prolonged, thrombocythaemia Bleeding tendency, thrombocytopenia, granulocytopenia, agranulocytosis, leukopenia, pancytopenia, aplastic anaemia. Other frequent causes of discontinuation included palpitation and diarrhoea both 1. The following side effects have been reported for Pletal. One tablet contains mg of cilostazol. Therefore, drugs inhibiting CYP3A4 e. Pletal mg tablets 2. Posology The recommended dosage of cilostazol is mg twice a day. Cilostazol is not a substitute for such treatments. An increased frequency of retardation of ossification of the sternum was observed in rabbits. Reporting of suspected adverse reactions. One tablet contains 50 mg or mg cilostazol. To view the changes to a medicine you must sign up and log in. Cilostazol inhibited mouse oocyte maturation in vitro, and in female mice caused a reversible impairment of fertility. Drug information contained herein may be time sensitive. Cilostazol per se may carry an increased risk of bleeding and pletal risk may be peltal by co-administration with any other agent with such potential.

As with other positive inotropic and vasodilator agents, cilostazol produced cardiovascular lesions in dogs. Posology The recommended dosage of cilostazol is mg twice a day. No dosage adjustment is necessary in patients with mild hepatic disease. Very common Common Gastritis. Musculoskeletal, connective tissue and bone disorders. To email a medicine you must sign up and log in. Possible side effects 5. However, some cases of pancytopenia and aplastic anaemia had a fatal outcome. If for any reason you have taken more Pletal tablets than you should, you may have signs and symptoms such as severe headache, diarrhoea, a fall in blood pressure and irregularities of your heartbeat. Rash, pruritus Eczema, skin eruptions, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria. Clopidogrel and other antiplatelet drugs Concomitant administration of cilostazol and clopidogrel did not have any effect on platelet count, prothrombin time PT or activated partial thromboplastin time aPTT. Paediatric population Safety and efficacy in children have not been established. If you stop taking Pletal the pain in your legs may come back or get worse. Name of the medicinal product 2. Pletal tablets should be taken 30 minutes before breakfast and the evening meal. Pletal tablets should be taken 30 minutes before breakfast and the evening meal, pletal. Information on acute overdose in humans is limited. There have been rare or very rare reports of haematological abnormalities including thrombocytopenia, leucopenia, agranulocytosis, plegal and pletal anaemia see section 4. Pletal absence of a warning for a given drug or drug combination in no way should be lletal to indicate that the drug or combination is safe, effective or appropriate for any given patient. Based on these data, no dose adjustment is necessary.